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Antibody

Key Stage 3

Meaning

An antibody is a chemical made by white blood cells that help fight infection.

Key Stage 4

Meaning

An antibody is a chemical made by lymphocytes that is used to fight pathogens.

About Antibodies

Antibodies attach themselves to chemicals known as antigens which are proteins found on the surfaces of different pathogens or other cells.
Some antibodies can directly damage or destroy a pathogen.
Some antibodies attach themselves to pathogens to make it easier for phagocytes to engulf and destroy them. They act like tags to tell the phagocytes which cells to attack.
When an organism is infected lymphocytes produce hundreds of different antibodies until one works.
Once a lymphocyte has produce a working antibody it will remember and reproduce it any time the same pathogen infects the organism.
If a patient's own antibodies are not able to get rid of a pathogen scientists can find and organism that makes antibodies that do work and copy them to be injected into the patient. These are called monoclonal antibodies.

References

AQA

Antibodies, pages 130, 131, GCSE Combined Science Trilogy; Biology, CGP, AQA'
Antibodies, pages 136, 137, GCSE Biology, CGP, AQA'
Antibodies, pages 32, 46, GCSE Combined Science; The Revision Guide, CGP, AQA'
Antibodies, pages 36, 49, GCSE Biology; The Revision Guide, CGP, AQA'
Antibodies, pages 55, 86, GCSE Combined Science Trilogy 1, Hodder, AQA'
Antibodies, pages 55, 87-8, GCSE Biology, Hodder, AQA'
Antibodies, pages 93, 106-109, GCSE Biology; Third Edition, Oxford University Press, AQA'
Antibodies; monoclonal, pages 97-101, GCSE Biology, Hodder, AQA'
Antibody, pages 116, 150-1, 158-9, 246, GCSE Biology; Student Book, Collins, AQA'
Antibody; monoclonal (mAB), pages 158-9, 161, 179, GCSE Biology; Student Book, Collins, AQA'

Edexcel

Antibodies, pages 114, 167, GCSE Biology, Pearson, Edexcel
Antibodies, pages 165-167, 169-172, 263, GCSE Biology, CGP, Edexcel
Antibodies, pages 41, 42, 61, GCSE Combined Science; The Revision Guide, CGP, Edexcel
Antibodies, pages 58-61, 89, GCSE Biology; The Revision Guide, CGP, Edexcel
Antibodies; monoclonal, pages 120-121, GCSE Biology, Pearson, Edexcel

OCR

Antibodies, pages 223-225, Gateway GCSE Biology, Oxford, OCR
Antibodies, pages 71, 72, Gateway GCSE Combined Science; The Revision Guide, CGP, OCR
Antibodies, pages 94, 95, 100, 101, Gateway GCSE Biology; The Revision Guide, CGP, OCR