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|[[File:DenaturedEnzyme.png|center|400px]]
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| style="height:20px; width:200px; text-align:center;" |This [[diagram]] shows an [[enzyme]] (the lock) and the [[substrate (Biology)|substrate]] (the key) fitting together. If the lock is '[[denaturation|denatured]]' the key no longer fits the lock and so the [[enzyme]] does not work.
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