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: When there is not enough [[water]] in the [[blood]] the [[Pituitary Gland|pituitary gland]] [[secrete]]s [[Anti-diuretic Hormone|anti-diuretic hormone]] which causes the [[Kidney Tubule|tubules]] allow [[water]] back into the [[blood]].
: When there is too much [[water]] in the [[blood]] the [[Pituitary Gland|pituitary gland]] stops [[secrete|secreting]] [[Anti-diuretic Hormone|anti-diuretic hormone]] which causes the [[Kidney Tubule|tubules]] stop allowing [[water]] back into the [[blood]].
: If [[osmoregulation]] fails and the body gains too much [[water]] (overhydration)the [[concentration]] of [[nutrient]]s, particularly [[Sodium Chloride]], will become too low preventing [[Impulse (Biology)|impulses]] in the [[neuron]]s while some [[Cell (Biology)|cells]] will swell causing the [[brain]] to get larger increasing the [[pressure]] inside the skull and damaging the [[brain]].
: If [[osmoregulation]] fails and the body loses too much [[water]] ([[dehydration]]) the [[concentration]] of [[nutrient]]s and waste products becomes too high which can cause the [[Metabolic Process|metabolic processes]] in [[Cell (Biology)|cells]] to slow or stop killing the [[organism]].