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===Meaning===
[[Denaturation]] is when an [[enzyme]] changes shape so they [[Substrate (Biology)|substrate]] can no longer fit in the [[Active Site|active site]].
===References===
====Edexcel====
:[https://www.amazon.co.uk/gp/product/1782948120/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782948120&linkCode=as2&tag=nrjc-21&linkId=dedef775c6a43dbb0a609441525adac0 ''Denaturation (enzymes), pages 37, 38, GCSE Biology, CGP, Edexcel '']