Changes

: People with [[Sickle Cell Anemia]] can have problems with the circulation in their limbs due to [[capillaries]] becoming blocked by sickle shaped [[Red Blood Cell|red blood cells]].

: [[Sickle Cell Anemia]] can also cause feelings of tiredness and fatigue in the [[muscle]]s as [[oxygen]] cannot be transported to the [[Cell (Biology)|cells]] that need them.

===References===

:[https://www.amazon.co.uk/gp/product/0008158754/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=0008158754&linkCode=as2&tag=nrjc-21&linkId=27ad53b0283feeff7fc5ae04a9e205f509 ''Sickle cell anemia, page 117, GCSE Biology; Student Book, Collins, AQA '']