Changes

: [[Water]] is removed from the [[blood]] and passed into [[Kidney Tubule|tubules]] in the [[kidney]]s. The [[water]] is then selectively reabsorbed into the [[blood]] depending on how much [[water]] is needed.

: [[Osmoregulation]] in the [[kidney]]s is affected by [[Anti-diuretic Hormone|anti-diuretic hormone]].

: When there is too much [[water]] in the [[blood]] the [[Pituitary Gland|pituitary gland]] stops [[secrete|secreting]] [[Anti-diuretic Hormone|anti-diuretic hormone]] which causes the [[Kidney Tubule|tubules]] stop allowing [[water]] back into the [[blood]].

: If [[osmoregulation]] fails and the body gains too much [[water]] (overhydration)the [[concentration]] of [[nutrient]]s, particularly [[Sodium Chloride]], will become too low preventing [[Impulse (Biology)|impulses]] in the [[neuron]]s while some [[Cell (Biology)|cells]] will swell causing the [[brain]] to get larger increasing the [[pressure]] inside the skull and damaging the [[brain]].