Difference between revisions of "Mutation"
(Created page with "==Key Stage 4== ===Meaning=== A mutation is a change to the DNA in a cell which causes a new variant of a gene. ===About Mutations=== : M...") |
|||
| (6 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
==Key Stage 4== | ==Key Stage 4== | ||
===Meaning=== | ===Meaning=== | ||
| − | A [[mutation]] is a change to the [[DNA]] in a [[Cell (Biology)|cell]] which causes a new | + | A [[mutation]] is a change to the [[DNA]] in a [[Cell (Biology)|cell]] which causes a new variant of a [[gene]]. |
===About Mutations=== | ===About Mutations=== | ||
| Line 7: | Line 7: | ||
: Most [[mutation]]s are errors which occur during [[DNA]] replication in [[Cell Division|cell division]]. However, some can occur due to [[DNA]] becoming damaged by [[Ionising Radiation|ionising radiation]]. | : Most [[mutation]]s are errors which occur during [[DNA]] replication in [[Cell Division|cell division]]. However, some can occur due to [[DNA]] becoming damaged by [[Ionising Radiation|ionising radiation]]. | ||
: [[Mutation]]s affect [[Gene Expression|gene expression]]. Since [[gene]]s act as templates for building [[protein]], if a [[gene]] has been altered by [[mutation]] the [[protein]]s will also be changed. | : [[Mutation]]s affect [[Gene Expression|gene expression]]. Since [[gene]]s act as templates for building [[protein]], if a [[gene]] has been altered by [[mutation]] the [[protein]]s will also be changed. | ||
| − | : [[Mutation]]s lead to the [[protein]]s, [[Coding DNA|coded]] for by a [[gene]], to have a different shape and function. A [[mutation]] may cause the [[Active Site|active site]] of an [[enzyme]] to change, leading to a [[substrate]] no longer fitting in the [[Active Site|active site]] or, in rare cases, a different [[substrate]] fitting the [[Active Site|active site]]. | + | : [[Mutation]]s lead to the [[protein]]s, [[Coding DNA|coded]] for by a [[gene]], to have a different shape and function. A [[mutation]] may cause the [[Active Site|active site]] of an [[enzyme]] to change, leading to a [[Substrate (Biology)|substrate]] no longer fitting in the [[Active Site|active site]] or, in rare cases, a different [[Substrate (Biology)|substrate]] fitting the [[Active Site|active site]]. |
| + | |||
| + | ===References=== | ||
| + | ====AQA==== | ||
| + | |||
| + | |||
| + | :[https://www.amazon.co.uk/gp/product/1782945563/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945563&linkCode=as2&tag=nrjc-21&linkId=9a1d023a374038e6072f33c4f3cf808b ''Deletions (mutations), page 86, GCSE Biology; The Revision Guide, CGP, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/0008158770/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=0008158770&linkCode=as2&tag=nrjc-21&linkId=ec31595e720e1529e49876c3866fff6e ''Mutation, gene or cell, page 122, GCSE Physics; Student Book, Collins, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782945598/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945598&linkCode=as2&tag=nrjc-21&linkId=ad276ad49df77ab4b40ab4fd0fe10090 ''Mutations, page 73, GCSE Combined Science; The Revision Guide, CGP, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1471851338/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1471851338&linkCode=as2&tag=nrjc-21&linkId=425855d5890466e47189e1c21b67a1ea ''Mutations, pages 187-8, 200, GCSE Biology, Hodder, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782946381/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782946381&linkCode=as2&tag=nrjc-21&linkId=5ec5fc3f6429e30c1d9ab9bca2bccf93 ''Mutations, pages 231, 232, GCSE Combined Science Trilogy; Biology, CGP, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782945954/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945954&linkCode=as2&tag=nrjc-21&linkId=100574c08fbbb64318256eb79ed61a76 ''Mutations, pages 249, 250, 283, GCSE Biology, CGP, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1471851362/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1471851362&linkCode=as2&tag=nrjc-21&linkId=7d78d70a2044ee9982dae010c94af92a ''Mutations, pages 48, 266, GCSE Combined Science Trilogy 2, Hodder, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/0198359373/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=0198359373&linkCode=as2&tag=nrjc-21&linkId=952a73bbb09d222ecc4b50d200679849 ''Mutations, pages 78, 114, 206-207, 220-221, GCSE Biology; Third Edition, Oxford University Press, AQA ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782945563/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945563&linkCode=as2&tag=nrjc-21&linkId=9a1d023a374038e6072f33c4f3cf808b ''Mutations, pages 86, 95, GCSE Biology; The Revision Guide, CGP, AQA ''] | ||
| + | |||
| + | ====Edexcel==== | ||
| + | |||
| + | :[https://www.amazon.co.uk/gp/product/1782945741/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945741&linkCode=as2&tag=nrjc-21&linkId=30da4f2178da182547b62a7329d13b57 ''Mutations, page 30, GCSE Combined Science; The Revision Guide, CGP, Edexcel ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782946748/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782946748&linkCode=as2&tag=nrjc-21&linkId=a4f0348fc37d0ba1bb52d27f8679581f ''Mutations, pages 35, 42, GCSE Biology; The Revision Guide, CGP, Edexcel ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1292120193/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1292120193&linkCode=as2&tag=nrjc-21&linkId=572df39392fb4200db8391d98ae6314e ''Mutations, pages 50-51, 351, 368, GCSE Combined Science, Pearson Edexcel ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1292120207/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1292120207&linkCode=as2&tag=nrjc-21&linkId=22455ff53961978667722edaa64c0be5 ''Mutations, pages 60, 70-71, GCSE Biology, Pearson, Edexcel ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1292120223/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1292120223&linkCode=as2&tag=nrjc-21&linkId=068ecf40278c32406a7f1c6e66751417 ''Mutations, pages 87, 106, GCSE Physics, Pearson Edexcel ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782948120/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782948120&linkCode=as2&tag=nrjc-21&linkId=dedef775c6a43dbb0a609441525adac0 ''Mutations, pages 93, 94, 118, 119, GCSE Biology, CGP, Edexcel ''] | ||
| + | |||
| + | ====OCR==== | ||
| + | :[https://www.amazon.co.uk/gp/product/1782945660/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945660&linkCode=as2&tag=nrjc-21&linkId=83aa4500ad7759e7f401a1c5ba5df758 ''Mutations (in DNA), pages 67, 73, Gateway GCSE Biology; The Revision Guide, CGP, OCR ''] | ||
| + | :[https://www.amazon.co.uk/gp/product/1782945695/ref=as_li_tl?ie=UTF8&camp=1634&creative=6738&creativeASIN=1782945695&linkCode=as2&tag=nrjc-21&linkId=ceafcc80bcad6b6754ee97a0c7ceea53 ''Mutations, pages 49, 54, Gateway GCSE Combined Science; The Revision Guide, CGP, OCR ''] | ||
| + | |||
| + | ==Beyond the Curriculum== | ||
| + | {{#ev:youtube|https://www.youtube.com/watch?v=vP8-5Bhd2ag}} | ||
Latest revision as of 06:36, 15 December 2019
Contents
Key Stage 4
Meaning
A mutation is a change to the DNA in a cell which causes a new variant of a gene.
About Mutations
- Mutations occur randomly so they cannot be predicted.
- Most mutations are errors which occur during DNA replication in cell division. However, some can occur due to DNA becoming damaged by ionising radiation.
- Mutations affect gene expression. Since genes act as templates for building protein, if a gene has been altered by mutation the proteins will also be changed.
- Mutations lead to the proteins, coded for by a gene, to have a different shape and function. A mutation may cause the active site of an enzyme to change, leading to a substrate no longer fitting in the active site or, in rare cases, a different substrate fitting the active site.
References
AQA
- Deletions (mutations), page 86, GCSE Biology; The Revision Guide, CGP, AQA
- Mutation, gene or cell, page 122, GCSE Physics; Student Book, Collins, AQA
- Mutations, page 73, GCSE Combined Science; The Revision Guide, CGP, AQA
- Mutations, pages 187-8, 200, GCSE Biology, Hodder, AQA
- Mutations, pages 231, 232, GCSE Combined Science Trilogy; Biology, CGP, AQA
- Mutations, pages 249, 250, 283, GCSE Biology, CGP, AQA
- Mutations, pages 48, 266, GCSE Combined Science Trilogy 2, Hodder, AQA
- Mutations, pages 78, 114, 206-207, 220-221, GCSE Biology; Third Edition, Oxford University Press, AQA
- Mutations, pages 86, 95, GCSE Biology; The Revision Guide, CGP, AQA
Edexcel
- Mutations, page 30, GCSE Combined Science; The Revision Guide, CGP, Edexcel
- Mutations, pages 35, 42, GCSE Biology; The Revision Guide, CGP, Edexcel
- Mutations, pages 50-51, 351, 368, GCSE Combined Science, Pearson Edexcel
- Mutations, pages 60, 70-71, GCSE Biology, Pearson, Edexcel
- Mutations, pages 87, 106, GCSE Physics, Pearson Edexcel
- Mutations, pages 93, 94, 118, 119, GCSE Biology, CGP, Edexcel
OCR
- Mutations (in DNA), pages 67, 73, Gateway GCSE Biology; The Revision Guide, CGP, OCR
- Mutations, pages 49, 54, Gateway GCSE Combined Science; The Revision Guide, CGP, OCR